Drug Identity
Active Ingredient
Simvastatin
Chemical Class
Lactone
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C10AA01
Status
Essential Medicine
What is Sivgit?
Uses
Simvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatin is used to lower blood levels of "...
How It Works
Chemical Class
Lactone
Pharmacological Group
on the basis of mechanism of action and also classified in Antilipemic Agent pharmacological group
Simvastatin also known as Synvinoline. It is of Synthetic origin and belongs to Lactone. It belongs to HMGCoA reductase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antilipemic Agent pharmacological group. The Molecular Weight of Simvastatin is 418.60.
How to Take It
1
Adult · PO
5 to 80 mg — 24 hourly
In evening, maintenance dose ranges 5-40 mg.
2
Adult
Scraped Dose
Take simvastatin exactly as prescribed. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medicati
3
Child
Not recommended in this age group
Safety Alerts
You should not take this medicine if you are allergic to simvastatin, or if: you have active liver disease
or you are pregnant or breastfeeding
The following drugs can increase your risk of serious muscle problems if you take them together with simvastatin
These drugs should not be used while you are taking this medicine: cyclosporine
an antibiotic - clarithromycin, erythromycin, telithromycin
Important Warnings
In rare cases, simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure
Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine
Never take simvastatin in larger amounts, or for longer than recommended by your doctor
Follow your doctor's dosing instructions very carefully
Taking too much of this medication may cause serious or life-threatening side effects
Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, diabetes, or a thyroid disorder, if you are of Chinese descent, or if you drink more than 2 alcoholic beverages daily
Simvastatin can harm an unborn baby or cause birth defects
Do not use if you are pregnant or planning to become pregnant
Side Effects
Get emergency medical help if you have signs of an allergic reaction to simvastatin (hivesdifficult breathingswelling in your face or throat) or a severe skin reaction (feversore throatburning eyesskin painred or purple skin rash with blistering and peeling). Simvastatin can cause the breakdown of muscle tissuewhich can lead to kidney failure. Call your doctor right away if you have unexplained muscle paintendernessor weakness especially if you also have feverunusual tirednessor dark urine. Also call your doctor at once if you have: signs of a kidney problem - little or no urinatingpainful or difficult urinationswelling in your feet or anklesfeeling tired or short of breath
Drug Interactions
Many drugs can interact with simvastatin. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment
especially: delavirdine
fenofibrate
or fluconazole. Your doctor may need to change your treatment plan if you use certain antibiotics or antifungal medicines
heart medication
antiviral medications such as hepatitis C medications
HIV/AIDS medications
or Paxlovid for COVID-19. This list is not complete and many other drugs can interact with simvastatin. This includes prescription and over-the-counter medicines
Storage
Tab Store Below 40°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 316.74
DRAP approved maximum price · per pack of 10 · approved 04 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
No retail prices recorded
Should you consider an alternative?
Other options containing Simvastatin, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Simvazaf
10mg
Rs 134Rs 13.4/unit
Below approved ceilingZAFA PHARMACEUTICAL LAB
Survive
10Mg
Rs 161.5Rs 16.15/unit
Below approved ceilingWERRICK PHARMACEUTICALS
Recol
10mg
Rs 215.3Rs 21.53/unit
Below approved ceilingNo DRAP alertsBARRETT HODGSON PAKISTAN
Simvazaf
20mg
Rs 237.8Rs 23.78/unit
Below approved ceilingZAFA PHARMACEUTICAL LAB
Survive
20Mg
Rs 304Rs 30.4/unit
Below approved ceilingWERRICK PHARMACEUTICALS
Zocor
10mg
Rs 307.8Rs 30.78/unit
Below approved ceilingOBS Pakistan Pvt. Ltd
Recol
20mg
Rs 339.4Rs 33.94/unit
Below approved ceilingNo DRAP alertsBARRETT HODGSON PAKISTAN
Zocor
20mg
Rs 613.7Rs 61.37/unit
Below approved ceilingOBS Pakistan Pvt. Ltd
Zocor
40mg
Rs 960.4Rs 96.04/unit
Below approved ceilingOBS Pakistan Pvt. Ltd
Nuista
10mg
Rs 434.9
BOSCH PHARMACEUTICALS (PVT) LTD.
Nuista
20mg
Rs 869.79
BOSCH PHARMACEUTICALS (PVT) LTD.
Nuista
40mg
Rs 1,630.86
BOSCH PHARMACEUTICALS (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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