Drug Identity
Active Ingredient
Cefotaxime
Chemical Class
Cephalosporin
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Suresef?
Uses
Cephradine is a first generation, semisynthetic analogue of natural cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminoce...
How It Works
Chemical Class
Cephalosporin
Pharmacological Group
on the basis of mechanism of action and also classified in Antibiotic, Cephalosporin pharmacological group
Cephradine also known as Cefradine. It is of Semi Synthetic origin and belongs to Cephalosporin. It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotic, Cephalosporin pharmacological group.The Molecular Weight of Cephradine is 349.40. Its pKa is 2.6, 7.3.
How to Take It
1
Adult · IM
1 to 2 g — As recommended.
2
Adult · IV
2 to 4 mg — 6 hourly
3
Adult · PO
250 to 500 mg — 12 hourly
Maximum dose: 4 g/day. Frequency may be increased to 3 times if needed.
4
Child · IV/IM
50 to 100 mg/kg — As recommended.
For Paeds of All Ages . given in 4 divided doses .This dose is for severe infections.(to maximum of
5
Child · P/O
75 to 100 mg/kg — 24 hourly
Otilis media
6
Child · PO
25 to 50 mg/kg — As recommended.
Given in 2-4 divided doses
Safety Alerts
Cephradine is contraindicated in conditions like Hypersensitivity
Important Warnings
Cephradine should be used with caution in patients with impaired kidney or liver function
Appropriate measure should be taken if secondary infection occurs
Side Effects
The severe or irreversible adverse effects of Cephradinewhich give rise to further complications include Pseudomembranous colitisHypersensitivity reactionsSeizuresSuperinfection.Cephradine produces potentially life-threatening effects which include ThrombophlebitisAnaphylactic reactions. which are responsible for the discontinuation of Cephradine therapy.The signs and symptoms that are produced after the acute over dosage of Cephradine include NauseaConvulsionsSevere diarrhea. The symptomatic adverse reactions produced by Cephradine are more or less tolerable and if they become severethey can be treated symptomaticallythese include NauseaDiarrheaSkin rashesVaginitisLocal pain.
Drug Interactions
Cephradine is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementEthacrynic AcidFrusemide or FurosemideConcomitant administeration leads to nephrotoxicityGentamicinNetilmicin (Sulphate)Pivmecillinam (HCl)Simultaneous administration of other Cephradine with Pivmecillinam (HCl) Tablets may produce a synergistic effect.ProbenecidProtamine (Sulphate)Protamine sulfate has been shown to be incompatible with Cephradine.Tobramycin These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Inj Store Below 40°C. Protect from Sunlight. Syrup, Caps Store in a well closed container, at room temperature, Below 30°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 88.42
DRAP approved maximum price · per unit · approved 21 Oct, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper unitRs 88.42
Should you consider an alternative?
Other options containing Cefotaxime, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Lenwin
500mg
Rs 45.45
GETZ PHARMA PAKISTAN (PVT) LTD.
Taxiron
125mg
Rs 55.5
No DRAP alertsPHARMEDIC (PVT) LTD.
Otid
250mg
Rs 76.5Rs 12.75/unit
SAMI PHARM (PVT) LTD.
Cefomerc
250mg
Rs 77
Below approved ceilingNo DRAP alertsMartin Dow Marker Limited
Lenwin
125mg/5ml
Rs 85.62
GETZ PHARMA PAKISTAN (PVT) LTD.
Wintax Iv/Im
250mg
Rs 85.65Rs 85.65/unit
No DRAP alertsBARRETT HODGSON PAKISTAN
Lenwin
1g
Rs 86.95
GETZ PHARMA PAKISTAN (PVT) LTD.
Tefotaxime
250mg
Rs 89.01
No DRAP alertsSeraph Pharmaceutical DML: 000860
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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