Drug Identity
Active Ingredient
Tacrolimus
Drug Class
Immunosuppressants
ATC Code
D11AH01, L04AD02
Status
Essential Medicine
What is Tacgraf?
Uses
Tacrolimus is used together with other medicines in people who have had a heart, kidney, liver, or lung transplant. Tacrolimus weakens yo...
How It Works
It is of Synthetic origin. The Molecular Weight of Tacrolimus is 804.00.
How to Take It
1
Adult · PO/IV-Inf
100 to 200 mcg/kg — 6 hourly
In liver transplant starting 6 hrs after transplantation.
2
Adult · PO/IV-Inf
150 to 300 mcg/kg — 6 hourly
In renal transplant starting 6 hrs after transplantation.
3
Adult
Scraped Dose
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may r
Safety Alerts
Avoid concurrent administration with ciclosporin (care if patient has previously received ciclosporin)
Important Warnings
Increased risk of infections, lymphoproliferative disorders, malignancies, neurotoxicity, QT-interval prolongation, UV light (avoid excessive exposure to sunlight and sunlamps)
Cardiomyopathy has been reported in children given tacrolimus after transplantation
Patients should be monitored carefully by echocardiography for hypertrophic changes
dose reduction or discontinuation should be considered if these occur
Monitor visual status, blood glucose, haematological and neurological parameters and whole blood 'trough' concentrations of tacrolimus (especially during episodes of diarrhoea), may affect performance of skilled tasks (e
Side Effects
Alopeciaanaemiaanorexiaanxietyarthralgiaascitesbile-duct abnormalitiesblood disorderscholestasisconvulsionconfusiondepressiondizzinessdyspneaelectrolyte disturbances
Drug Interactions
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take
which may increase side effects or make the medications less effective. Tacrolimus can harm your kidneys
especially if you also use certain medicines for infections
cancer
osteoporosis
organ transplant rejection
bowel disorders
high blood pressure
Storage
Caps Store at room temperature. Protect from Moisture. Inj Store at room temperature, Below 25°C. Refrigeration and Freezing is not recommended. Protect from Sunlight.
Price Intelligence
Rs 989.4
Servaid observed price · as of 30 July 2026
Prices across sources
ServaidRs 989.4
Should you consider an alternative?
Other options containing Tacrolimus, and what they are not.You pay Rs 464 more than the cheapest equivalent
Identical active ingredient at the same strength. Cheapest per unit first.
Inograf
0.5mg
Rs 525Rs 52.5/unit
Lowest price per unitBelow approved ceilingPLATINUM PHARMACEUTICAL
Tacmas
0.5mg
Rs 1,366.82 ceiling
The Schazoo Pharmaceutical Laboratories (Pvt.) Ltd.
Tacrolim
0.5mg
Rs 1,080.69 ceiling
SAFE PHARMACEUTICAL (PVT) LTD.
Tacrover
0.5mg
Rs 1,783.59 ceiling
No DRAP alertsRadiant Pharma (Pvt.) Ltd.,
Grafsol
0.5mg
Rs 9,603.66 ceiling
Pharmasol (Pvt) Ltd.
Aerograf
0.5mg
Rs 1,497.85 ceiling
Glitz Pharma
Imucurb
0.5mg
Rs 1,410 ceiling
No DRAP alertsARP (PVT) Limited
Arilio
0.5mg
Rs 1,886.76 ceiling
SAMI PHARMACEUTICALS (PVT) LTD.
T-Mus
0.5mg
Rs 1,700.79 ceiling
STANDPHARM PAKISTAN (PVT) LTD.
Taclekin
0.5mg
Rs 1,528.97 ceiling
No DRAP alertsNAVEGAL LABORATORIES
Unigraf
0.5mg
Rs 1,753.35 ceiling
KAIZEN PHARMACEUTICALS PVT LTD.
Culimus
0.5mg
Rs 1,488.75 ceiling
No DRAP alertsCunningham Pharmaceuticals (Pvt.) Ltd.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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