Drug Identity
Active Ingredient
Azathioprine
Chemical Class
Purine Imidazole
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
L04AX01
Status
Essential Medicine
What is Thioprim?
Uses
Azathioprine weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection h...
How It Works
Chemical Class
Purine Imidazole
Pharmacological Group
on the basis of mechanism of action and also classified in Antidotes and Immunosuppressant Agent pharmacological group
It is of Synthetic origin and belongs to Purine Imidazole. It belongs to Antimetabolites (DNA acting) pharmacological group on the basis of mechanism of action and also classified in Antidotes and Immunosuppressant Agent pharmacological group.The Molecular Weight of Azathioprine is 277.30. Its pKa is 8.2.
How to Take It
1
Adult · IV
50 to 300 mg — As recommended.
Initially for once
2
Adult · PO
200 to 300 mg — As recommended.
Initially for once.
3
Adult · PO,IV
50 to 300 mg — 24 hourly
Maintenance, As Required
4
Adult
Scraped Dose
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using azathioprine. Follow all directions on your prescription label and read all med
5
Child · Intra Venous
1 to 4 mg/kg — 24 hourly
6
Child · Oral
1 to 4 mg/kg — 24 hourly
Safety Alerts
You should not take azathioprine if you are allergic to azathioprine
You should not use azathioprine to treat rheumatoid arthritis if you are pregnant
This medicine can harm an unborn baby
Use effective birth control to prevent pregnancy while using this medicine
Azathioprine may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal
Important Warnings
Azathioprine may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal
This has occurred mainly in teenagers and young men with Crohn's disease or ulcerative colitis
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hivesdifficult breathingswelling of your facelipstongueor throat. Azathioprine may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speechthoughtvisionor muscle movement. These symptoms may start gradually and get worse quickly. Stop using azathioprine and call your doctor right away if you have any of these symptoms of lymphoma : feverswollen glandsbody achesnight sweatsnot feeling wellpale skinrash
Drug Interactions
Tell your doctor about all your current medicines. Many drugs can affect azathioprine
especially: allopurinol
febuxostat
or ribavirin . This list is not complete and many other drugs may affect azathioprine. This includes prescription and over-the-counter medicines
vitamins
and herbal products . Not all possible drug interactions are listed here.
Storage
Tab, Inj Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 197.69
DRAP approved maximum price · per pack of 10 · approved 21 Oct, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 10Rs 197.69
Should you consider an alternative?
Other options containing Azathioprine, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Amorin
50Mg
Rs 270.8Rs 27.08/unit
Lowest price per unitMASS PHARMA (PVT) LTD.
Imuran
50mg
Rs 1,092.5Rs 43.7/unit
GlaxoSmithKline PAKISTAN
Pharmazorine
50mg
Rs 1,850.1
No DRAP alertsPHARMEDIC (PVT) LTD.
Asteprine
50mg
Rs 3,516.04 ceiling
No DRAP alertsHamaz Pharmaceuticals (Pvt) Ltd.
Demard
50mg
Rs 205.59 ceiling
BIO LABS (PVT) LTD.
Theomed
50mg
Rs 1,821.24 ceiling
Mediate Pharmaceutical Pvt Ltd
Imuprine
50mg
Rs 2,137.45 ceiling
No DRAP alertsHIRANIS PHARMACEUTICALS PVT LTD
Imulite
50mg
Rs 3,516.04 ceiling
No DRAP alertsCRYSTOLITE PHARMACEUTICALS
Dysmorin
50mg
Rs 3,516.04 ceiling
No DRAP alertsDyson Research Laboratories (Pvt.) Ltd
Neuthoprin
50mg
Rs 3,516.04 ceiling
NEUTRO PHARMA (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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