Tokom

Tokom Injection Im/Iv

Cefotaxime

NEUTRO PHARMA (PVT) LTD.

Drug Identity

Active Ingredient
Cefotaxime
Drug Class
Other Beta-Lactam, Cephalosporins & Penems
ATC Code
J01DD01
Status
Essential Medicine

What is Tokom?

infection
prevent infection in people having certain types of surgery

How It Works

Inject deep IM into large muscle mass. IV: Inject direct IV over 3-5 min. Infuse intermittent infusion over 30 min. Reconstitute each 0.5, 1, or 2 gm vial with 10 ml of SWFI. Shake to dissolve. For intermittent IV infusion, further dilute in 50-100 ml of D5W or NS. IM: Reconstitute each 500 mg vial with 2 ml SWFI or bacteriostatic water for injection, each 1 gm vial with 3 ml diluent and each 2 gm vial with 5 ml diluent. Shake to dissolve. Compatibility: D5 1/4 NS, 05 1h NS, D5NS, D5W, 010W, LR, NS.

How to Take It

1
Adult · 0.5-2 pre-operatively for prophylaxis against infection in surgery.
1 g — 24 hourly
2
Adult · IM
0.25 to 0.5 g — As recommended.
3
Adult · IV,IM
1 to 2 g — 24 hourly
Once daily or in two divided doses. Max. dose: 4 g/day. Given by IV infusion over atleast 30 minutes.
4
Child · For prevention of secondary cases of mennigococcal meningitis
0 to 125 mg — As recommended.
5
Child · Intra Venous
20 to 50 mg/kg — 24 hourly
For serve infections up to 80mg/kg daily should be given

Safety Alerts

You should not take ceftriaxone if you are allergic to cefazolin or any other cephalosporin antibiotic ( cefdinir , cefalexin, Keflex, Omnicef, and others)
Do not use ceftriaxone in a child without a doctor's advice , and never give more than the child's prescribed dose
Ceftriaxone injection could be dangerous when given to a newborn baby with any intravenous medicines that contain calcium, including total parental nutrition (TPN)
Tell your doctor if you have ever had: liver or kidney disease
gallbladder disease

Important Warnings

Hypersensitivity, severe renal failure
Monitor blood count if treatment exceeds 10 days

Side Effects

Abdominal discomfortagranulocytosisallergic reactionsanaphylaxisaplastic anaemiablood disordersconfusiondisturbances in liver enzymesdizzinesseosinophiliahaemolytic anaemiaheadachehypertonialeucopenianervousness

Drug Interactions

Loop diuretics
aminoglycosides
probenecid.

Pregnancy & Lactation

Pregnancy
No evidence of harm
Lactation
Caution advised

Storage

Dry Powder for Inj Store at room temperature. Protect from Sunlight.

Price Intelligence

Rs 110.89
DRAP approved maximum price · per unit · approved 27 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper unitRs 110.89

Should you consider an alternative?

Other options containing Cefotaxime, and what they are not.

For pharma professionalsCompany, market and opportunity intelligence

Company

453
brands
394
molecules
2
alerts

Prices as of 30 July 2026 · DRAP ceiling as of 30 July 2026 · schema v3-SKU

For medicine intelligence and professional reference only. Not medical advice.