Drug Identity
Active Ingredient
Tramadol
Drug Class
Pain Management
What is Tonoflex?
Uses
Tramadol (HCl) is a centrally-acting analgesic with a unique, dual mechanism of action, within the CNS; it exerts agonistic properties at...
How It Works
Continuous or intermittent in dextrose 5% or sodium chloride 0.9% or LR.
How to Take It
1
Adult · PO,IV,IM
50 to 100 mg — 6 hourly
maximun oral dose is 400mg, IV injection given over 2 to 3min
2
Adult · Rectal
100 mg — 4 hourly
maximun oral dose is 400mg, IV injection given over 2 to 3min
3
Child · Intra Muscular
1 to 2.5 mg/kg — 8 hourly
-
4
Child · Oral
1 to 2.5 mg/kg — 8 hourly
-
5
Child · Slow IV
1 to 2.5 mg/kg — 8 hourly
-
Safety Alerts
Acute respiratory depression, comatose patients, head injury and raised intracranial pressure (opioid analgesics interfere with pupillary responses vital for neurological assessment), risk of paralytic ileus, acute intoxication with alcohol, hypnotics, analgesics or other CNS-acting drugs
Important Warnings
Renal or hepatic impairment, adrenocortical insufficiency and hypothyroidism (reduced dose), asthma (avoid during an acute attack), convulsive disorders, diseases of the biliary tract, hypotension, elderly and debilitated patients (reduced dose), impaired respiratory function (avoid in chronic obstructive pulmonary disease), inflammatory bowel disorders, myasthenia gravis, obstructive bowel disorders, prostatic hypertrophy, shock, urethral stenosis, history of opioid abuse
Side Effects
Biliary spasmbradycardiaconfusionconstipationdependencedifficulty with micturitiondizzinessdrowsinessdry mouthdysphoriaeuphoriaflushinghallucinationsheadachehypotension and muscle rigidity (larger doses)
Drug Interactions
Tranquillizers
hypnotics and other substances which act on the central nervous system
MAO inhibitors.
Pregnancy & Lactation
Pregnancy
Positive evidence of risk: Respiratory depression and withdrawal symptoms in the neonate; gastric stasis and inhalation pneumonia in the mother if opioid analgesics are used during labour and
Lactation
: Contraindicated or not recommended.
Storage
Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 74.1
DVAGO observed price · as of 30 July 2026
Rs 74.1 per unit
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 244.3
DVAGORs 74.1
Should you consider an alternative?
Other options containing Tramadol, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Votadol
50mg
Rs 177.3Rs 17.73/unit
HORIZON PHARMACEUTICALS
Tramal
50Mg
Rs 237.5Rs 23.75/unit
SEARLE PAKISTAN (PVT) LTD.
Tramal
100Mg
Rs 546.3Rs 109.26/unit
SEARLE PAKISTAN (PVT) LTD.
Trumed
50mg
Rs 134
NEUTRO PHARMA
Trumed
100mg
Rs 179.5
NEUTRO PHARMA
Tylagesic
37.50mg
Rs 196.79
No DRAP alertsBRYON PHARMACEUTICALS (PVT) LTD.
Pantra
Rs 200
MULLER & PHIPPS PAKISTAN (PVT) LTD.
Tramal
Rs 369.45
SEARLE
Campex
Rs 551.4
AKHAI
Campex
50mg
Rs 775.5
AKHAI
Tylagesic
37.5mg
Rs 196.79 ceiling
No DRAP alertsBRYON PHARMACEUTICALS (PVT) LTD.
Misadol
100mg
Rs 230.24 ceiling
No DRAP alerts
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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