Drug Identity
Active Ingredient
Tramadol
Drug Class
Pain Management
Chemical Class
Opioid
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Tonoflexp?
Uses
Tramadol (HCl) is a centrally-acting analgesic with a unique, dual mechanism of action, within the CNS; it exerts agonistic properties at...
How It Works
Chemical Class
Opioid
Pharmacological Group
on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group
It belongs to Opioid. It belongs to Amine reuptake inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group. The Molecular Weight of Tramadol (HCl) is 299.80. Its pKa is 9.41.
How to Take It
1
Adult · PO,IV,IM
50 to 100 mg — 6 hourly
maximun oral dose is 400mg, IV injection given over 2 to 3min
2
Adult · Rectal
100 mg — 4 hourly
maximun oral dose is 400mg, IV injection given over 2 to 3min
3
Child · Intra Muscular
1 to 2.5 mg/kg — 8 hourly
-
4
Child · Oral
1 to 2.5 mg/kg — 8 hourly
-
5
Child · Slow IV
1 to 2.5 mg/kg — 8 hourly
-
Safety Alerts
Acute respiratory depression, comatose patients, head injury and raised intracranial pressure (opioid analgesics interfere with pupillary responses vital for neurological assessment), risk of paralytic ileus, acute intoxication with alcohol, hypnotics, analgesics or other CNS-acting drugs
Important Warnings
Renal or hepatic impairment, adrenocortical insufficiency and hypothyroidism (reduced dose), asthma (avoid during an acute attack), convulsive disorders, diseases of the biliary tract, hypotension, elderly and debilitated patients (reduced dose), impaired respiratory function (avoid in chronic obstructive pulmonary disease), inflammatory bowel disorders, myasthenia gravis, obstructive bowel disorders, prostatic hypertrophy, shock, urethral stenosis, history of opioid abuse
Side Effects
Malaisebiliary spasmbradycardiaconfusionconstipationdependencedifficulty with micturitiondizzinessdrowsinessdry mouthdysphoriaeuphoriaflushinghallucinationsheadache
Drug Interactions
Tranquillizers
hypnotics and other substances which act on the central nervous system
MAO inhibitors.
Pregnancy & Lactation
Pregnancy
Risk of Embryotoxic; avoid.
Lactation
Contraindicated
Storage
Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 154.8
DVAGO observed price · as of 30 July 2026
No approved ceiling matched to this exact pack and strength.
Prices across sources
DVAGORs 154.8
ServaidRs 141.5
Should you consider an alternative?
Other options containing Tramadol, and what they are not.You pay Rs 9 more than the cheapest equivalent
Identical active ingredient at the same strength. Cheapest per unit first.
Krotam
37.5mg
Rs 237.5Rs 23.75/unit
Lowest price per unitNo DRAP alertsMartin Dow
Pantraplus
37.5mg
Rs 146
GETZ PHARMA PAKISTAN (PVT) LTD.
Acetra
37.5mg
Rs 187
Below approved ceilingAmarant Pharmaceuticals Private Limited
Diagesicextra
37.5mg
Rs 199.5
WILSONS PHARMACEUTICALS
Tramapar
37.5mg
Rs 199.5
EFROZE CHEMICAL INDUSTRIES (PVT) LTD.
Duragesict
37.5mg
Rs 204.3
TABROS
Frendolp
37.5mg
Rs 212.93
HIGH-Q
Calfinaplus
37.5mg
Rs 230
No DRAP alertsAGP
Tramalplus
37.5mg
Rs 250
SEARLE PAKISTAN (PVT.) LTD.
Ekcel
37.5mg
Rs 380
No DRAP alertsDYSON R L
Simgesic
37.5mg
Rs 712.6
No DRAP alertsCELL
Dosteril
37.5mg
Rs 750
HORIZON
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
303
brands
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molecules
1
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