300 MCGBlood Cell Deficiecy

TOPNEUTER

TOPNEUTER 300 MCG ING

Rhug-Csf)

Merixil Pharma DSL: DHO-ISB-1745 pc 1 units

Drug Identity

Active Ingredient

Rhug-Csf)

Drug Class

Immunostimulants

ATC Code

L03AA02

Status

Essential Medicine

What is TOPNEUTER?

Uses

Filgrastim is used to treat neutropenia (lack of certain white blood cells) in patients receiving certain cancer medications, undergoing ...

How It Works

For IV infusion give continuously over 30 min or intermittently in Glucose 5%; for a filgrastim concentration of less than 1 500 000 units/ml(15 mcg/ml) albumin solution is added to produce a final albumin concentration of 2 mg/ml; should not be diluted to a filgrastim concentration of less than 200 000 units/ml (2 mcg/ml) and should not be diluted with sodium chloride solution. For SC dose larger than 1 ml, divide and give in more than one site.

How to Take It

Adult · SC,IV Inf

5 ug/ kg — 24 hourly

As an adjunct to chemotherapy, starting not less than 24 hrs after the last dose of antineoplstic.

Safety Alerts

Severe congenital neutropenia (Kostmanns syndrome) with abnormal cytogenetics

Important Warnings

Patients with pre-malignant or malignant myeloid conditions

Withdraw in patients who develop pulmonary infiltration, Sickle-cell disease, distinguish carefully from other haematological disorders

Full blood counts including differential white cell and platelet counts should be monitored

Spleen size should be monitored during treatment risk of splenomegaly and rupture

Side Effects

Anorexiaanaemiadysuriaepistaxisexacerbation of rheumatoid arthritishaematuriahepatomegalymucositisosteoporosisproteinuriapseudogoutraised uric acidsplenic enlargement (rarelyspleen rupture)transient decrease in blood glucose

Drug Interactions

Fluorouracil.

Pregnancy & Lactation

Pregnancy

Risk cannot be ruled out, should not be used during pregnancy unless the potential benefit outweighs the risk.

Lactation

Caution advised or effect undetermined.

Storage

Inj (reconstituted soln) Store in refrigerator. Do not Freeze. Protect from Sunlight. Use within 24 hrs if kept at room temperature.

Price Intelligence

Rs 3,401

DVAGO observed price · as of 30 July 2026

Rs 3,401 per unit

~28% below the approved ceiling, per unit

DRAP approved ceiling: Rs 4,727.25 (per unit)

0You pay: Rs 3,401/unitRs 4,727.25/unit

Reg. 084991 · approved 27 Jul, 2026

Prices across sources

DVAGORs 3,401

DRAPper unitRs 4,727.25

Should you consider an alternative?

Other options containing Rhug-Csf), and what they are not.

Identical active ingredient at the same strength. Cheapest per unit first.

Amgofil

300mcg

Rs 5,736.36 ceiling

No DRAP alertsAmgomed

Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.

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