Traszeptin

Do not administer as an IV push or bolus only IV infusion loading doses or infused over 90 min. Reconstitute each 440 mg vial with 20 ml of bacteriostatic water for injection, containing benzyl alcohol 1.1% as a preservative, to yield a multi-dose solution containing trastuzumab 21 mg/ml. In patientswith hyper-sensitivity to benzyl alcohol, reconstitute with 20 ml of SWFI without preservative to yield a single-use solution. Using a sterile syringe, slowly inject 20 ml of the diluents into the vial containing the lyophilizied cake of trastuzumab. The streamof diluent should be directed into the lyophilized cake. Swirlthe vial gently to aid reconstitution. Do not shake. Slight foaming may be present upon reconstitution. Allow the vialto stand undisturbed for approximately 5min.