Drug Identity
Active Ingredient
Verapamil
Chemical Class
Phenyl Valeronitrile
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C08DA01
Status
Essential Medicine
What is Zeyar?
Uses
Verapamil is an oral and parenteral calcium-channel blocking (CCB) agent. Verapamil (HCl) is useful for the treatment of angina, hyperten...
How It Works
Chemical Class
Phenyl Valeronitrile
Pharmacological Group
on the basis of mechanism of action and also classified in Anti arrhythmic agents pharmacological group
Verapamil (HCl) also known as Iproveratril HCl. It is of Synthetic origin and belongs to Phenyl Valeronitrile. It belongs to Calcium L-channel antagonist pharmacological group on the basis of mechanism of action and also classified in Anti arrhythmic agents pharmacological group. The Molecular Weight of Verapamil (HCl) is 491.07.
How to Take It
1
Adult · PO
40 to 120 mg — 8 hourly
2
Adult
Scraped Dose
There is no specific antidote for verapamil overdosage; treatment should be supportive. Delayed pharmacodynamic consequences may occur with extended-release formulations, and patients should be obs
3
Child · Oral
2 to 3 mg/kg — 8 hourly
-
Safety Alerts
Verapamil (HCl) is contraindicated in conditions like Congestive Heart failure, Bradycardia, Platelet dysfunction, Cardiogenic shock, Symptomatic hypotension, Sick sinus syndrome
Important Warnings
Verapamil should be used with caution in patients with liver or kidney impairment
Consider decrease in dose of calcium channel blockers and monitor drug response in cirrhosis patients
Side Effects
Serious adverse reactions are uncommon when verapamil HCl therapy is initiated with upward dose titration within the recommended single and total daily dose. See WARNINGS for discussion of heart failurehypotensionelevated liver enzymesAV blockand rapid ventricular response. Reversible (upon discontinuation of verapamil) non-obstructiveparalytic ileus has been infrequently reported in association with the use of verapamil. In clinical trials involving 285 hypertensive patients on verapamil hydrochloride extended-release capsules for greater than 1 week the following adverse reactions were reported in greater than 1.0% of the patients: In clinical trials of other formulations of verapamil HCl (N = 4954) the following reactions have occurred at rates greater than 1.0%: In clinical trials related to the control of ventricular response in digitalized patients who had atrial fibrillation or atrial flutterventricular rate below 50/min at rest occurred in 15% of patients and asymptomatic hypotension occurred in 5% of patients. The following reactionsreported in 1.0% or less of patientsoccurred under conditions (open trialsmarketing experience) where a causal relationship is uncertainthey are listed to alert the physician to a possible relationship: Cardiovascular: angina pectorisatrioventricular dissociationchest painclaudication
Drug Interactions
Verapamil (HCl) is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAcebutololVerapamil may enhance the hypotensive effect of Acebutolol. Bradycardia and signs of heart failure have also been reported. Verapamil may decrease the metabolism
via CYP isoenzymes
of Acebutolol.ModerateManagement Though usually safe and effective during concomitant use
monitor for increased evidence of bradycardia
hypotension
or signs of heart failure during concomitant use of beta-blockers and nondihydropyridine calcium channel blockers. Ophthalmic beta-blockers are likely of little concern. Though usually safe and effective during concomitant use
monitor for increased evidence of bradycardia
Storage
Tab, Inj Store Below 40°C. Protect from Sunlight.
Price Intelligence
Rs 187.63
DRAP approved maximum price · per pack of 50 · approved 05 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 50Rs 187.63
Should you consider an alternative?
Other options containing Verapamil, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Calan
40Mg
Rs 178.5Rs 3.57/unit
Lowest price per unitBelow approved ceilingSEARLE PAKISTAN (PVT) LTD.
Zavera
40mg
Rs 115.92 ceiling
ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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