Drug Identity
Active Ingredient
Zuclopenthixol
Chemical Class
Xanthine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
N05AF05
Status
Essential Medicine
What is Zuclodept?
Uses
Zuclopenthixol is a tranquillizer, similar to chlorpromazine. Zuclopenthixol is used in the treatment of schizophrenia.
How It Works
Chemical Class
Xanthine
Pharmacological Group
on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Thioxanthene pharmacological group
It is of Synthetic origin and belongs to Xanthine. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Thioxanthene pharmacological group. The Molecular Weight of Zuclopenthixol is 400.90. Its pKa is 3.4, 6.1.
How to Take It
1
Adult · IM
200 to 400 mg — As recommended.
Every 2-4 Week
2
Adult · PO
20 to 30 mg — 24 hourly
Initial
3
Adult · PO
20 to 50 mg — 8 hourly
Maintenance
4
Child
Not recommended in this age group
Safety Alerts
Zuclopenthixol is contraindicated in conditions like Alcohol dependence, Parkinsonism, Pheochromocytoma, Coma, CNS depression
Important Warnings
Zuclopenthixol should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal impairment, prostatic hypertrophy
Photosensitization may occur, caution patients to take appropriate measures (e
wear protective clothing or sunscreen) against exposure to sunlight or UV light
Discontinue use at least 48 hrs before myelography
Side Effects
Zuclopenthixol produces potentially life-threatening effects which include FeverNeuroleptic Malignant SyndromeHypertonicity. which are responsible for the discontinuation of Zuclopenthixol therapy.The signs and symptoms that are produced after the acute overdosage of Zuclopenthixol include ConvulsionsComaHypothermiaSomnolenceExtrapyramidal effects. The symptomatic adverse reactions produced by Zuclopenthixol are more or less tolerable and if they become severethey can be treated symptomaticallythese include TachycardiaParkinsonismAkathisiaLoss of libidoDystonic reactionsMenstrual irregularityOrthostatic hypotension
Drug Interactions
Zuclopenthixol is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholGuanethidineMetoclopramide (HCl)ProchlorperazineVORICONAZOLEAdditive QTc prolongation may occur. Consider alternate therapy or use caution and monitor for QTc prolongation These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab, Inj Store Below 25°C. Protect from Sunlight.
Price Intelligence
Rs 637.98
DRAP approved maximum price · per unit · approved 12 Aug, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
No retail prices recorded
Should you consider an alternative?
Other options containing Zuclopenthixol, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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