Drug Identity
Active Ingredient
Bisoprolol
Drug Class
Beta Blocking Agent
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C07AB07
Status
Essential Medicine
What is Corbis H?
Uses
Hydrochlorothiazide is a prototype drug of thiazide diuretics. Hydrochlorothiazide is antihypertensive agent. It increases the urination ...
How It Works
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group
It is of Synthetic origin and belongs to Thiazide. It belongs to NaCl cotransport inhibitor pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group. The Molecular Weight of Hydrochlorothiazide is 297.74. Its pKa is 7.9, 9.2.
How to Take It
1
Adult · PO
25 to 100 mg — 24 hourly
As Required
2
Child · Oral
2.5 mg/kg — 12 hourly
Safety Alerts
Acute or decompensated heart failure requiring intravenous inotropes, sino-atrial block, 2nd or 3rd degree AV block (without pacemaker), severe bradycardia, uncontrolled heart failure, cardiogenic shock, severe peripheral arterial disease, hypotension, metabolic acidosis, untreated pheochromocytoma, severe asthma or COPD
Important Warnings
AV block, heart failure (avoid if un-controlled), peripheral arterial circulatory disorders (avoid if severe), Prinzmetals angina, myasthenia gravis, Ischaemic heart disease, withdraw gradually, history of bronchospasm, diabetes, hyperthyroidism, renal or hepatic impairment, psoriasis, elderly, consider withdrawal before elective surgery, anaphylaxis risk due to increased sensitivity to allergens, Always withdraw gradually over period of 1-2 weeks IV administration requires cardiac and blood pressure monitoring
Dose adjustment in renal impairment: with oral use max 50mg daily if eGFR15-35 ml/minute/1
max 25mg daily or 50 mg on alternate days if eGFR less than 15 ml/minute/1
With intravenous use max 10 mg on alternate days if eGFR15-35 ml/minute/1
10 mg every 4 days if eGFR less than 15 ml/minute/1
Side Effects
Cardiovascular effects including bradycardiapostural hypotensionincreased AV blockcardiac arrhythmiasRaynauds phenomenoncold extremitiessexual dysfunctionGI upsetsleep and CNS disturbancesskin reactionsfatigueparaesthesiaperipheral neuropathyarthralgiamyopathy
Drug Interactions
Ca+ + antagonists
antihypertensives including centrally acting agents (e.g. clonidine)
antiarrhythmics
antipsychotics
TCADs
MAOIs
fluvoxamine
barbiturates
Pregnancy & Lactation
Pregnancy
Avoid, risk cannot be ruled out.
Lactation
Contraindicated or not recommended.
Storage
Store in a well closed container, at room temperature. Protect from Moisture and Heat. Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 249
DVAGO observed price · per pack of 20 · as of 30 July 2026
Rs 12.45 per unit
No approved ceiling matched to this exact pack and strength.
Prices across sources
DVAGOper pack of 20Rs 249
Should you consider an alternative?
Other options containing Bisoprolol, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Valvozidplus
5mg
Rs 138.74
PACIFIC PHARMACEUTICALS LTD.
Sopral Plus
5mg
Rs 193.07 ceiling
No DRAP alertsBRYON PHARMACEUTICALS (PVT) LTD.
Sopral Plus
10mg
Rs 420 ceiling
No DRAP alertsBRYON PHARMACEUTICALS (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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