Drug Identity
Active Ingredient
Norethisterone
Chemical Class
Steroid
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
G03AC01, G03DC02
Status
Essential Medicine
What is Eforeth-N?
Uses
This belongs to the group of medicines known as progestogens. Norethisterone and its acetate and enantate esters are progestogens derived...
How It Works
Chemical Class
Steroid
Pharmacological Group
on the basis of mechanism of action and also classified in Sex Hormones and Contraceptive Hormonal pharmacological group
Norethisterone also known as Northidrone. . It is of Synthetic origin and belongs to Steroid. It belongs to Progesterone agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones and Contraceptive Hormonal pharmacological group.The Molecular Weight of Norethisterone is 298.40.
How to Take It
1
Adult · IM
200 mg — As recommended.
This dose provide contraception for 8 weeks. The dose is for Norethisterone Enanthate.
2
Adult · PO
2.5 to 10 mg — 24 hourly
As Required. This dose is for Norethisterone (Acetate, Heptanoate).
Safety Alerts
Norethisterone is contraindicated in conditions like Acute renal failure,Epilepsy,Breast cancer,Cardiovascular disease,Hepatitis,Liver carcinoma,Amenorrhoea,Herpes gestations,Skin diseases,Bronchial asthma,Hypersensitivity to the drug
Important Warnings
Norethisterone should be used with caution in patients with medical history, including any allergies (especially drug allergies), abnormal vaginal bleeding, liver, kidney or heart disease, cancer of the breast or genitals, missed abortion, blood clots, seizures, migraine, asthma, depression or diabetes
Limit alcohol, as this may increase side effects of this drug
It is not recommended to take it in early pregnancy
Norethisterone Enanthate should be used with caution in patients with cardiovascular or renal impairment, diabetes mellitus, asthma, epilepsy, and migraine, or other conditions which may be aggravated by fluid retention
They should also be used with care in persons with a history of depression
High doses should be used with caution in patients susceptible to thromboembolism
It should not be given to the patients with undiagnosed vaginal bleeding, nor to those with a history or current high risk of arterial disease and should generally be avoided in hepatic impairment, especially if severe
Side Effects
The severe or irreversible adverse effects of Norethisteronewhich give rise to further complications include HepatitisCataractCholestatic jaundiceOptic neuritisHyperglycemiaHypertensionMental disturbancesRetinal thrombosisUterine myomataDecreased libidoVaginitisGalactorrheaBreakthrough bleedingLeukorrhea
Drug Interactions
Norethisterone is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCyclosporin AEstrogens ConjugatedGriseofulvinPhenytoin (Na)Rifampicin These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store in a well closed container, Below 40°C.
Price Intelligence
Rs 51.72
DRAP approved maximum price · per pack of 30 · approved 11 Aug, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 30Rs 51.72
Should you consider an alternative?
Other options containing Norethisterone, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Just-N
5Mg
Rs 308.7Rs 10.29/unit
Lowest price per unitMASS PHARMA (PVT) LTD.
Primolut N
5mg
Rs 274.2
Below approved ceilingNo DRAP alertsOBS Pharma (Pvt) Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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