Drug Identity
Active Ingredient
Norethisterone
Drug Class
Progestogen
Chemical Class
Steroid
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
G03AC01, G03DC02
Status
Essential Medicine
What is Primolut N?
Uses
This belongs to the group of medicines known as progestogens. Norethisterone and its acetate and enantate esters are progestogens derived...
How It Works
Chemical Class
Steroid
Pharmacological Group
on the basis of mechanism of action and also classified in Sex Hormones and Contraceptive Hormonal pharmacological group
Norethisterone also known as Northidrone. . It is of Synthetic origin and belongs to Steroid. It belongs to Progesterone agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones and Contraceptive Hormonal pharmacological group.The Molecular Weight of Norethisterone is 298.40.
How to Take It
1
Adult · IM
200 mg — As recommended.
This dose provide contraception for 8 weeks. The dose is for Norethisterone Enanthate.
2
Adult · PO
2.5 to 10 mg — 24 hourly
As Required. This dose is for Norethisterone (Acetate, Heptanoate).
Safety Alerts
Severe arterial disease, undiagnosed vaginal bleeding and acute porphyria, history during pregnancy of idiopathic jaundice, severe pruritus, or pemphigoid gestations, incomplete miscarriage, missed miscarriage
Avoid in hepatic impairment
Avoid in active liver disease including disorders of hepaticexcretion (e
Dublin-Johnson or Rotor Syndromes),infective hepatitis (until liver function returns to normal) and liver tumours and lactation
Important Warnings
Renal impairment, conditions that may worsen with fluid retention, epilepsy, hypertension, migraine, asthma, or cardiac dysfunction, susceptible to thromboembolism (particular caution with high dose, history of depression
Progestogens can decrease glucose tolerance and patients with diabetes should be monitored closely
While using as contraceptive wait 6 weeks post-partum if lactating
Side Effects
Irregularprolonged or heavy vaginal bleeding during first 2 or 3 cyclesmenstrual disturbancespremenstrual-like syndrome (including bloatingfluid retentionbreast tenderness)weight changenauseaheadachedizzinessinsomniadrowsinessdepressionchange in libidoalso skin reactions (including urticaria
Drug Interactions
Norethisterone is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCyclosporin AEstrogens ConjugatedGriseofulvinPhenytoin (Na)Rifampicin These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store in a well closed container, Below 40°C.
Price Intelligence
Rs 274.2
Servaid observed price · as of 30 July 2026
Prices across sources
DRAPper pack of 30Rs 380.13
ServaidRs 274.2
Should you consider an alternative?
Other options containing Norethisterone, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Just-N
5Mg
Rs 308.7Rs 10.29/unit
Lowest price per unitMASS PHARMA (PVT) LTD.
Eforeth-N
5mg
Rs 51.72 ceiling
EFROZE CHEMICAL INDUSTRIES (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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