Drug Identity
Active Ingredient
Hydrocortisone N.F
Drug Class
Hormone Regulators
ATC Code
A01AC03, A07EA02, C05AA01, D07AA02, D07XA01, H02AB09, S01BA02, S01CB03, S02BA01
Status
Essential Medicine
What is Hyzonate?
Uses
Hydrocortisone butyrate (Locoid Lipocream, Locoid Lotion) is used to help skin conditions that respond to steroid creams. Locoid lotion c...
How It Works
Hydrocortisone sodium succinate may be administered by IM or IV.IV bolus: Dilute to 50 mg/ml and give over.30 seconds to several min.IV intermittent infusion: Dilute to 1 mg/ml and give over 20-30 min.
How to Take It
1
Adult · IV
100 to 500 mg — 8 hourly
2
Adult · Ophthalmic
1 % — As recommended.
As Required
3
Adult · Topical
0.1 to 2 % — 8 hourly
As Required
4
Child · Intra Muscular
5 mg/kg — 6 hourly
-
5
Child · Intra Venous
5 mg/kg — 6 hourly
-
6
Child · Opthalmic
1 % — As recommended.
As Required
Safety Alerts
Systemic fungal infections unless specific anti-infective therapy is used, head injury, stroke
Important Warnings
Active infections not controlled by antibiotics, latent or active amoebiasis, history of TB, septicaemia, symptoms may be masked, avoid or maintain extreme cautions in chickenpox, measles, psychiatric disorders, renal impairment, hepatic failure, cirrhosis, active peptic ulcer, myasthenia gravis, previous steroid myopathy, osteoporosis, epilepsy, hypothyroidism, diabetes, adrenal suppression, hypertension, recent MI, congestive heart failure, thromboembolic disorders, glaucoma, corneal perforation
Withdraw gradually, withdrawal symptoms may include fever, myalgia, arthralgia, rhinitis, itchy skin nodules and weight loss
Side Effects
Endocrine irregularities including menstrual problemscushingoid stateadrenal suppressiongrowth suppression in childrenincreased susceptibility to infectionincreased severity of infectionfluid/electrolyte disturbancehypertensionnegative proteinnitrogen andcalcium balancemyopathytendon ruptureosteoporosisosteonecrosis and fracturesimpaired wound healing
Drug Interactions
Live vaccines or other vaccines
anticoagulants
hypoglycaemia agents
antihypertensives
diuretics
erythromycin
rifamycin
amphotericin
Pregnancy & Lactation
Pregnancy
Caution advised
Lactation
Caution advised
Storage
Inj, Oral Susp, Dental Paste, Cream, Oint Store Below 40°C. Do not Freeze. Protect from Sunlight. Suppositories Store at room temperature, Below 15°C or in refrigerator. Do not Freeze. Protect from Sunlight and Moisture. Tab Store at room temperature.
Price Intelligence
Rs 163
Servaid observed price · as of 30 July 2026
Prices across sources
ServaidRs 163
DRAPper unitRs 251.73
Should you consider an alternative?
Other options containing Hydrocortisone N.F, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Gemcot
1%
Rs 19.01
BIO PHARMA
Hydrocortisone
10mg
Rs 21.87
Below approved ceilingXENON PHARMACEUTICALS (PVT) LTD.
Cortival
1% 10g
Rs 49.1Rs 49.1/unit
No DRAP alertsVALOR PHARMA
Cortival
Rs 49.1
No DRAP alertsVALOR PHARMACEUTICALS
Cortival
10g
Rs 49.1
No DRAP alertsVALOR
Hydrocortisone
10g
Rs 57.24Rs 57.24/unit
ZAFA PHARMACEUTICAL LAB
Hydrocortisone
Rs 60.25
ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
Hydrosodsuc
100mg
Rs 94.42
Below approved ceilingZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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