Drug Identity
Active Ingredient
Hydrochlorothiazide
Drug Class
Angiotensin-Ii Antagonists, Combinations
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C03AA03
Status
Essential Medicine
What is Losaan-H?
Uses
Hydrochlorothiazide is a prototype drug of thiazide diuretics. Hydrochlorothiazide is antihypertensive agent. It increases the urination ...
How It Works
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group
It is of Synthetic origin and belongs to Thiazide. It belongs to NaCl cotransport inhibitor pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group. The Molecular Weight of Hydrochlorothiazide is 297.74. Its pKa is 7.9, 9.2.
How to Take It
1
Adult · PO
25 to 100 mg — 24 hourly
As Required
2
Child · Oral
2.5 mg/kg — 12 hourly
Safety Alerts
Hepatic impairment, anuria, moderate to severe renal impairment, dialysis, intravascular volume depletion
Important Warnings
Hepatic impairment, renal impairment, intravascular volume depletion, renal artery stenosis, obstructive valvular disease, aortic stenosis, outflow obstruction, cardiomyopathy, SLE, gout, obstructive valvular disease
Monitor serum electrolytes
Side Effects
Hyperkalaemiaangioedemasymptomatic hypotension including dizziness particularly in patients with intravascular volume depletione.g. those taking high-dose diureticsarthralgiarhinitisflatulenceorthostatic effectsdiarrhoealiver function abnormalitiesmyalgiahypertriglyceridaemiamigraineurticariapruritus
Drug Interactions
Barbiturates
narcotics
antidiabetic agents
cholestyramine
colestipol
corticosteroids
ACTH
adrenaline
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Storage
Store in a well closed container, at room temperature. Protect from Moisture and Heat. Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 1,186.76
DRAP approved maximum price · per pack of 20 · approved 04 Nov, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
No retail prices recorded
Should you consider an alternative?
Other options containing Hydrochlorothiazide, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Qsartan Plus
12.5Mg
Rs 211.1Rs 21.11/unit
HIGH-Q INTERNATIONAL.
Losar Plus
50Mg 12.5Mg
Rs 254.1Rs 25.41/unit
PLATINUM PHARMACEUTICAL
Co-A2A
50mg 12.5mg
Rs 256.5Rs 25.65/unit
WILSONS PHARMACEUTICALS
Xavor-Diu
50Mg 12.5Mg
Rs 260.3Rs 26.03/unit
No DRAP alertsFEROZSONS LABORATORIES
Co-Eziday
100Mg 25Mg
Rs 340.8Rs 34.08/unit
WERRICK PHARMACEUTICALS
Xavordiu
12.5mg
Rs 175
No DRAP alertsFEROZSONS
Xavordiu
25mg
Rs 239
No DRAP alertsFEROZSONS
Coeziday
25mg
Rs 250
Werrick Pharmaceuticals Pakistan
Coa2A
50mg
Rs 256.5
WILSONS PHARMACEUTICALS
Losarplus
50mg
Rs 267.5
Below approved ceilingPLATINUM
Xavordiu
50mg
Rs 274
No DRAP alertsFEROZSONS
Giozard
12.5mg
Rs 330
No DRAP alertsP.D.H. PHARMACEUTICALS (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
234
brands
189
molecules
2
alerts