Drug Identity
Active Ingredient
Mannitol
Drug Class
Solutions Producing Osmotic Diuresis
Chemical Class
Sugar Alcohol
ATC Code
A06AD16, B05BC01, B05CX04, R05CB16, V04CX04
Status
Essential Medicine
What is Mactol?
Uses
Mannitol is a diuretic that is used to reduce swelling and pressure inside the eye or around the brain. Mannitol is also used to help you...
How It Works
Chemical Class
Sugar Alcohol
Mannitol also known as Manna sugar and Mannite. It is of Synthetic origin and belongs to Sugar Alcohol. The Molecular Weight of Mannitol is 182.20. It is weakly acidic drug, 5.07% solution of the drug is isotonic.
How to Take It
1
Adult · IV Inf
0.2 g/ kg/dose — As recommended.
Test Dose, Max. 12.5gm over 3-5 min, If there is no diuresis within 2 hrs. discontinue mannitol
2
Adult · IV Inf
0.25 to 0.5 g/ kg/dose — 6 hourly
Maintenance dose
3
Adult · IV Inf
0.5 to 1 g/ kg/dose — As recommended.
Initial dose
4
Adult · IV Inf
10 to 20 % — 24 hourly
5
Child
0.25 to 0 g/ug — As recommended.
6
Child · IV Infusion
16.66 to 66.66 mg/kg.min — As recommended.
Once for 30 Minutes .Can be repeated
Safety Alerts
Severe renal disease, dehydration, active intra cranial bleeding, severe pulmonary oedema
Important Warnings
Cardio-vascular and renal status should be evaluated
Side Effects
Congestive heart failureheadacheconvulsionsdizzinessrashelectrolyte balance disturbanceshyponatraemiaGI disturbancepolyurea.
Drug Interactions
Mannitol can harm your kidneys
especially if you also use certain medicines for infections
cancer
osteoporosis
organ transplant rejection
bowel disorders
high blood pressure
or pain or arthritis (including Advil
Storage
Inj Store Below 40°C. Do not Freeze. Protect from Sunlight.
Price Intelligence
Rs 270.53
DRAP approved maximum price · per 500ml · approved 23 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper 500mlRs 270.53
Should you consider an alternative?
Other options containing Mannitol, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Steriflutol
500ml
Rs 168.95
No DRAP alertsFRONTIER DEXTROSE LTD
Mannilyte
20% 500ml
Rs 206.48Rs 206.48/unit
OTSUKA PAKISTAN PVT LIMITED
Mannilyte
500ml
Rs 206.48
OTSUKA PAKISTAN LTD.
Flowtol
100ml
Rs 252.04
No DRAP alertsMEDIFLOW
Flowtol
Rs 252.04 ceiling
No DRAP alertsMediflow Pharmaceutical (Pvt) Ltd.
Maritol
20g
Rs 237.37 ceiling
NEUTRO PHARMA (PVT) LTD.
Maritol
100ml
Rs 109.71 ceiling
NEUTRO PHARMA (PVT) LTD.
Uniretic
Rs 252.04 ceiling
No DRAP alertsUnisa Pharmaceutical Industries Limited
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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