Drug Identity
Active Ingredient
Mefloquine
Chemical Class
Sulphonamide
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Melofen?
Uses
Sulfadoxine is antibacterial, belongs to Sulphonamide. Sulfadoxine is a long-acting drug with a very broad spectrum of activity Sulfadoxi...
How It Works
Chemical Class
Sulphonamide
Pharmacological Group
on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group
Sulfadoxine also known as sulphadoxine. It is of Synthetic origin and belongs to Sulphonamide. It belongs to Dihyropteroate synthetase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group. The Molecular Weight of Sulfadoxine is 310.30. Its pKa is 6.3.
How to Take It
1
Adult · PO
1500 mg — As recommended.
Single dose in combination with Pyrimethamine 75 mg.
2
Child · Oral
33.33 mg/kg — As recommended.
For Once, Dose for Paeds of 4-12 Yrs.
Safety Alerts
Sulfadoxine is contraindicated in conditions like Blood dyscrasias, Renal diseases, Hypersensitivity
Important Warnings
Sulfadoxine should be used only if clearly needed during pregnancy
It should be used with caution in patients with pre-existing blood disorders, anemia, liver disease, kidney disease, severe allergies, asthma or a history of seizures or any allergy, especially to sulfa medications
Side Effects
The severe or irreversible adverse effects of Sulfadoxinewhich give rise to further complications include HepatitisPneumonitis. Sulfadoxine produces potentially life-threatening effects which include Mucocutaneous reaction. which are responsible for the discontinuation of Sulfadoxine therapy. The signs and symptoms that are produced after the acute overdosage of Sulfadoxine include NauseaVomitingConvulsionsExcitationAnorexiaHematological toxicity. The symptomatic adverse reactions produced by Sulfadoxine are more or less tolerable and if they become severethey can be treated symptomaticallythese include HeadacheFatigueFeverRashesStomatitisPruritus
Drug Interactions
Sulfadoxine is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementChloroquineChloroquineMefloquine (HCl)Phenytoin (Na)Thiopentone (Na)TrimethoprimWarfarin (Na)Xylitol These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store Below 40°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 1,692.97
DRAP approved maximum price · per pack of 30 · approved 24 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 30Rs 1,692.97
Should you consider an alternative?
Other options containing Mefloquine, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Fansidar
+ Pyrimethamine
Rs 70.84
No DRAP alertsMartin Dow Limited
Fansidar
15ml
+ Pyrimethamine
Rs 70.84
No DRAP alertsMartin Dow Limited
FANSIDAR
25mg
+ Pyrimethamine
Rs 1,428
Below approved ceilingNo DRAP alertsMartin Dow Limited
Fansidar
500mg
+ Pyrimethamine
Rs 1,428
Below approved ceilingNo DRAP alertsMartin Dow Limited
Irene
25mg
+ Pyrimethamine
Rs 13.21 ceiling
No DRAP alertsZephyr Pharmatec (pvt) limited
Irene
500mg
+ Pyrimethamine
Rs 13.21 ceiling
No DRAP alertsZEPHYR PHARMATEC
Scot’s Antimalarial
50mg
+ Pyrimethamine
Rs 1,495.72 ceiling
No DRAP alertsSCOTMANN PHARMACEUTICALS
Maladar
500mg
+ Pyrimethamine
Rs 1,561.81 ceiling
EFROZE CHEMICAL INDUSTRIES (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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