Drug Identity
Active Ingredient
Inh
Drug Class
General
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Rifinah?
Uses
Rifampicin belongs to the group of complex macrocyclic antibiotic. Rifampicin is a zwitterionic. Rifampicin results from a condensation r...
How It Works
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group
Rifampicin also known as Rifampin. It is of Synthetic origin and belongs to Rifamycin. It belongs to rRNA polymerase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group. The Molecular Weight of Rifampicin is 822.90. Its pKa is 1.7, 7.9.
How to Take It
1
Adult · PO
450 to 600 mg — As recommended.
In 2-4 div.doses. Maximum dose: 600mg. Give 30 min before breakfast. Duration may vary according to indication.
2
Child · Oral
10 to 20 mg/kg — 24 hourly
Max 60mg/day
Safety Alerts
Previous hypersensitivity to any rifamycin, patients with previous isoniazid associated hepatic injury or other severe adverse reactions with isoniazid
Important Warnings
Patients with active chronic liver disease or severe renal dysfunction
Isoniazid crosses the placental barrier and passes into maternal breast milk, observe neonates, breast fed infants of isoniazid treated mothers for any evidence of adverse effects, caution patients against intentional or accidental interruption of daily dosage regimen, since rare renal hypersensitivity reactions have been reported when therapy is resumed
Urine, faeces, saliva, sputum, sweat and tears may be coloured red-orange
Side Effects
Anaphylactoid reactionsheartburnepigastric dis-tressanorexianauseavomitingdiarrhoeasore mouthrashpruritusurticariaeosinophiliathrombocytopeniamuscular weaknesspain in extremities
Drug Interactions
Rifampicin induces hepatic microsomal enzymes that metabolize a wide variety of drugs e.g. metoprolol
propranolol
quinidine
corticosteroids
contraceptives
oral anticoagulants
oral sulfonylureas. The effectiveness of isoniazid may be decreased when administered with corticosteroid. The effects of benzodiazepines may be increased. The hepatic toxicity of both isoniazid and/or rifampicin may be increased when administered concomitantly.
Pregnancy & Lactation
Pregnancy
Caution advised, use only if potential benefit outweighs risk
Lactation
Caution advised
Storage
Inj (reconstituted soln) Store at room temperature. Use within 24 hrs if kept at room temperature. Tab, Caps, Susp Store in a well closed container, Below 40°C. Protect from Sunlight, Moisture and Heat.
Price Intelligence
Rs 151.53
DRAP approved maximum price · per 50ml · approved 01 Jul, 2024
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
No retail prices recorded
Should you consider an alternative?
Other options containing Inh, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Unerif
150mg
Rs 3.71
No DRAP alertsUNEXO LABS (PVT) LTD.
Mycosin
450mg
Rs 13.6
No DRAP alertsMS SIZA INTERNATIONAL PVT LTD.
Unerif
300mg
Rs 17.09
No DRAP alertsUNEXO LABS (PVT) LTD.
Rimactal INH
300mg 150mg
Rs 45.6Rs 4.56/unit
GLOBAL PHARMACEUTICALS
Rimactal INH
300mg
Rs 45.6
Below approved ceilingGlobal Pharmaceuticals Pvt Ltd
Rifampicin
100mg/5ml
Rs 64.46
DOSACO LABORATORIES
Rimactal
Rs 91.8Rs 9.18/unit
GLOBAL PHARMACEUTICALS
Rimactal
300mg
Rs 91.8
Below approved ceilingGlobal Pharmaceuticals Pvt Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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