Drug Identity
Active Ingredient
Sulfadoxin
Chemical Class
Pyrimidine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
P01BD01
Status
Essential Medicine
What is Sinofen?
Uses
Pyrimethamine is an antiparasite medicine that helps prevent parasites from growing and reproducing in the body. Pyrimethamine is used in...
How It Works
Chemical Class
Pyrimidine
Pharmacological Group
on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group
It is of Synthetic origin and belongs to Pyrimidine. It belongs to Dihydrofolate reductase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group. The Molecular Weight of Pyrimethamine is 248.70. Its pKa is 7.3.
How to Take It
1
Adult · PO
25 mg — As recommended.
Once in a Week
2
Adult
Scraped Dose
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended. Your dosage a
3
Child · Oral
0.5 mg/kg — 24 hourly
Double dose for 1st 3 days
Safety Alerts
You should not use pyrimethamine if you are allergic to it, or if you have: a blood cell disorder called megaloblastic anemia that has been caused by folate ( folic acid ) deficiency
To make sure pyrimethamine is safe for you, tell your doctor if you have ever had: seizures (especially if you take phenytoin )
or if you are malnourished
Using pyrimethamine during pregnancy could harm the unborn baby
Use effective birth control to prevent pregnancy while taking pyrimethamine, and tell your doctor if you become pregnant
Important Warnings
You should not use pyrimethamine if you have a blood cell disorder called megaloblastic anemia that has been caused by folate deficiency
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hivesdifficult breathingswelling of your facelipstongueor throat. Pyrimethamine may cause serious side effects. Stop using pyrimethamine and call your doctor at once if you have: sore throatswelling in your tonguepale skineasy bruisingpurple spots under your skinthe first sign of any skin rashno matter how mildblood in your urinefevercold or flu symptoms
Drug Interactions
Tell your doctor about all your current medicines and any you start or stop using
especially: methotrexate
phenytoin
or a sulfa drug. This list is not complete. Other drugs may interact with pyrimethamine
including prescription and over-the-counter medicines
vitamins
and herbal products . Not all possible interactions are listed in this medication guide.
Storage
Tab Store in a well closed container, Below 40°C. Protect from Sunlight.
Price Intelligence
Rs 62.33
DRAP approved maximum price · per pack of 10 · approved 29 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 10Rs 62.33
Should you consider an alternative?
Other options containing Sulfadoxin, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Irene
500mg
+ Sulfadoxine
Rs 13.21
No DRAP alertsZEPHYR PHARMATEC
Fansidar
15ml
+ Sulfadoxine
Rs 70.84
No DRAP alertsMartin Dow Limited
FANSIDAR
25mg
+ Sulfadoxine
Rs 1,428
Below approved ceilingNo DRAP alertsMartin Dow Limited
Fansidar
+ Sulfadoxine
Rs 1,428
No DRAP alertsMartin Dow Limited
Fansidar
500mg
+ Sulfadoxine
Rs 4,097.41
Below approved ceilingNo DRAP alertsMartin Dow Limited
Irene
25mg
+ Sulfadoxine
Rs 13.21 ceiling
No DRAP alertsZephyr Pharmatec (pvt) limited
Maladar
500mg
+ Sulfadoxine
Rs 1,561.81 ceiling
EFROZE CHEMICAL INDUSTRIES (PVT) LTD.
Falcicure
500mg
+ Sulfadoxine
Rs 15.42 ceiling
S.J & G. Fazul Ellahie (pvt) limited.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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