Drug Identity
Active Ingredient
Imipramine
Drug Class
Antidepressants
Chemical Class
Tricyclic amines
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Tofranil?
Uses
Trimipramine is a tricyclic antidepressant that is used to treat symptoms of depression. Trimipramine may also be used for purposes not l...
How It Works
Chemical Class
Tricyclic amines
Pharmacological Group
on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant pharmacological group
It is of Synthetic origin and belongs to Tricyclic amines. It belongs to Amine uptake inhibitor pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant pharmacological group. The Molecular Weight of Imipramine (HCl) is 316.90. It is strongly acidic drug and Its pKa is 9.4.
How to Take It
1
Adult · PO
75 mg — 24 hourly
Gradually increased to 150 to 200mg
2
Adult
Scraped Dose
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. It may ta
3
Child · For children 6 to 7 years (20-25kg)
25 mg — As recommended.
4
Child · For children aged 8 to 11 years (25-35kg)
50 — As recommended.
5
Child · Oral
1 to 2 mg/kg — 24 hourly
Recommended for 5-12 Years Children at Bed Time
Safety Alerts
Acute porphyrias, arrhythmia, immediate recovery period after myocardial infarction, during the manic phase of bipolar disorder, heart block
Important Warnings
Cardiovascular disease, diabetes, epilepsy, chronic constipation, history of bipolar disorder, history of mania and psychosis, hyperthyroidism, prostatic hypertrophy, increased intra-ocular pressure, patients with a significant risk of suicide, phaeochromocytoma, susceptibility to angle-closure glaucoma, urinary retention, hepatic impairment (contraindicated if severe),concurrent ECT
Withdraw gradually
Side Effects
Agitationalopeciaanorexiaanxietyarrhythmiablurred visionfatigueflushingheadachepalpitationrestlessnesschillsconfusionconvulsionsdelusions
Drug Interactions
21 days of MAOls. Other antidepressants
St. Johns Wort
tramadol
drugs that prolong the QT interval (e.g. anti-arrhythmics)
moxifloxacin
anticonvulsants
diltiazem
verapamil
Pregnancy & Lactation
Pregnancy
Avoid unless potential benefit outweighs risk
Lactation
Contraindicated, avoid
Storage
Tab Store in a well closed container, at room temperature.
Price Intelligence
Rs 28.5
DVAGO observed price · per pack of 10 · as of 30 July 2026
Rs 2.85 per unit
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 364
DVAGOper pack of 10Rs 28.5
Should you consider an alternative?
Other options containing Imipramine, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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