Drug Identity
Active Ingredient
Tramadol
Drug Class
Pain Management
Chemical Class
Opioid
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Tonoflex-P?
Uses
Tramadol (HCl) is a centrally-acting analgesic with a unique, dual mechanism of action, within the CNS; it exerts agonistic properties at...
How It Works
Chemical Class
Opioid
Pharmacological Group
on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group
It belongs to Opioid. It belongs to Amine reuptake inhibitor pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group. The Molecular Weight of Tramadol (HCl) is 299.80. Its pKa is 9.41.
How to Take It
1
Adult · PO,IV,IM
50 to 100 mg — 6 hourly
maximun oral dose is 400mg, IV injection given over 2 to 3min
2
Adult · Rectal
100 mg — 4 hourly
maximun oral dose is 400mg, IV injection given over 2 to 3min
3
Child · Intra Muscular
1 to 2.5 mg/kg — 8 hourly
-
4
Child · Oral
1 to 2.5 mg/kg — 8 hourly
-
5
Child · Slow IV
1 to 2.5 mg/kg — 8 hourly
-
Safety Alerts
Acute respiratory depression, comatose patients, head injury and raised intracranial pressure (opioid analgesics interfere with pupillary responses vital for neurological assessment), risk of paralytic ileus, acute intoxication with alcohol, hypnotics, analgesics or other CNS-acting drugs
Important Warnings
Renal or hepatic impairment, adrenocortical insufficiency and hypothyroidism (reduced dose), asthma (avoid during an acute attack), convulsive disorders, diseases of the biliary tract, hypotension, elderly and debilitated patients (reduced dose), impaired respiratory function (avoid in chronic obstructive pulmonary disease), inflammatory bowel disorders, myasthenia gravis, obstructive bowel disorders, prostatic hypertrophy, shock, urethral stenosis, history of opioid abuse
Side Effects
Malaisebiliary spasmbradycardiaconfusionconstipationdependencedifficulty with micturitiondizzinessdrowsinessdry mouthdysphoriaeuphoriaflushinghallucinationsheadache
Drug Interactions
Tranquillizers
hypnotics and other substances which act on the central nervous system
MAO inhibitors.
Pregnancy & Lactation
Pregnancy
Risk of Embryotoxic; avoid.
Lactation
Contraindicated
Storage
Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 456
DVAGO observed price · per pack of 20 · as of 30 July 2026
Rs 22.8 per unit
No approved ceiling matched to this exact pack and strength.
Prices across sources
DVAGOper pack of 20Rs 456
ServaidRs 141.5
Should you consider an alternative?
Other options containing Tramadol, and what they are not.You pay Rs 269 more than the cheapest equivalent
Identical active ingredient at the same strength. Cheapest per unit first.
Acetra
37.5mg 325mg
Rs 187Rs 18.7/unit
Lowest price per unitAMARANT HEALTHCARE
Ekcel
37.5mg 325mg
Rs 380Rs 19/unit
No DRAP alertsDYSON RESEARCH LABORATORIES
Diagesic Extra
37.5mg 325mg
Rs 199.5Rs 19.95/unit
WILSONS PHARMACEUTICALS
Tramapar
37.5mg 325mg
Rs 199.5Rs 19.95/unit
Efroze Chemicals Industries Private Ltd
Frendol-P
37.5Mg 325Mg
Rs 202.3Rs 20.23/unit
HIGH-Q INTERNATIONAL.
Duragesic-T
37.5mg 325mg
Rs 204.3Rs 20.43/unit
TABROS PHARMA
Calfina Plus
37.5Mg 325Mg
Rs 218.5Rs 21.85/unit
No DRAP alertsAGP PHARMA
Pantra Plus
37.5Mg 325Mg
Rs 228Rs 22.8/unit
GETZ PHARMA PAKISTAN
Tramal Plus
37.5Mg 325Mg
Rs 237.5Rs 23.75/unit
SEARLE PAKISTAN (PVT) LTD.
Dosteril
37.5Mg 325Mg
Rs 712.5Rs 23.75/unit
HORIZON PHARMACEUTICALS
Simgesic
37.5mg 325mg
Rs 712.6Rs 35.63/unit
No DRAP alertsCELL LABORATORIES PVT. LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
Often Bought Together
Tramal Plus — Tramal Plus Tablets 37.5Mg+325Mg (1 Box = 1 Strip) (1 Strip = 10 Tablets)Rs 237.5Synflex — Synflex Tablets 550Mg (1 Strip = 10 Tablets)Rs 284.7Mecutec — Mecutec Tablets 7.5Mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)Rs 152Frendol-P — Frendol-P Tablets 37.5Mg+325Mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)Rs 202.3Moxtu — Moxtu Tablets 15Mg (1 Strip = 10 Tablets)Rs 237.5
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