Drug Identity
Active Ingredient
Zidovudine Usp 100Mg
Drug Class
Antivirals For Systemic Use
Chemical Class
Thymidine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
J05AF01
Status
Essential Medicine
What is Zidovir?
Uses
Zidovudine is an antiviral medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Zidovudine is ...
How It Works
Chemical Class
Thymidine
Pharmacological Group
on the basis of mechanism of action and also classified in Antiviral Agents pharmacological group
Zidovudine also known as AZT. It is of Synthetic origin and belongs to Thymidine. It belongs to Reverse transcriptase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antiviral Agents pharmacological group. The Molecular Weight of Zidovudine is 267.24. Its pKa is 9.68.
How to Take It
1
Adult · PO
2.857 mg/kg — 8 hourly
Initial
2
Adult · PO
3.571 to 4.286 mg/kg — 12 hourly
Maintenance
3
Child · Oral
7.05 to 8.46 mg/kg — 6 hourly
-
Safety Alerts
: Acute porphorias, low neutrophil cell counts or low haemoglobin levels, neonates with hyperbilirubinaemia or increased transaminase levels
Important Warnings
Elderly, lactic acidosis, risk of haematological toxicity particularly with high dose and advanced disease, vitamin B12 deficiency (increased risk of neutropenia)
Perform blood tests at least every 2 weeks (weekly for infusion) for first three months of therapy and at least monthly thereafter it patient has advanced disease
Adjust dose if anaemia or myelosuppression occurs or is present
Renal or hepatic impairment, pancreatitis, risk of immune reactivation syndrome in patients with severe immune deficiency within first few weeks or months of starting combination antiretroviral therapy, Pregnancy under 14 weeks gestation (only if benefit to mother outweighs risk to foetus)
Discontinue if aminotransferase levels rapidly elevating or with progressive hepatomegaly or metabolic lactic acidosis of unknown aetiology
Advise patients to report benign digestive symptoms, respiratory symptoms or neurological symptoms indicative of lactic acidosis development
Risk of osteonecrosis
monitor for signs of joint pain or immobility
Side Effects
Anaemiaanxietychest painconvulsionsdepressiondizzinessdrowsinessgynaecomastiainfluenza-like symptomslactic acidosislipodystrophyloss of mental acuitymyopathyneuropathyparaesthesia
Drug Interactions
Chronic administration of analgesics
particularly paracetamol. Drugs affecting hepatic glucuronidation or inhibiting hepatic microsomal enzymes
other potentially nephrotoxic or myelosuppressive drugs
Probenecid
monitor closely for haematological toxicity
Phenytoin
ribavirin
stavudine
Storage
Inj (reconstituted soln) Store at room temperature or refrigerator. Use within 24 hrs if refrigerated and within 8 hrs if kept at room temperature. Oral Syrup Store Between 15°C-25°C. Protect from Sunlight. Tab, Caps Store at room temperature, Below 30°C. Refrigeration and Freezing is not recommended. Protect from Sunlight and Moisture.
Price Intelligence
Rs 660.1
DRAP approved maximum price · per pack of 30 · approved 23 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 30Rs 660.1
Should you consider an alternative?
Other options containing Zidovudine Usp 100Mg, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Zeedo
5ml
Rs 437.4
HILTON PHARMA (PVT) LIMITED
Zeedo
50mg
Rs 437.4 ceiling
HILTON PHARMA (PVT) LIMITED
Zeedo
100mg
Rs 3,551.68 ceiling
HILTON PHARMA (PVT) LIMITED
Lamizid
150mg
+ Lamivudine
Rs 6,861.26
BOSCH PHARMACEUTICALS (PVT) LTD.
Lamizid
300mg
+ Lamivudine
Rs 6,861.26 ceiling
BOSCH PHARMACEUTICALS (PVT) LTD.
Duovir
150mg
+ Lamivudine
Rs 5,811.81 ceiling
No DRAP alertsAJ Mirza Pharma Pvt Ltd
Lamozid
150mg
+ Lamivudine, Lamuvudine
Rs 3,176.37 ceiling
NABIQASIM INDUSTRIES (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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