Drug Identity
Active Ingredient
Trimethoprim
Drug Class
Sulfonamides And Trimethoprim
ATC Code
J01EA01
Status
Essential Medicine
What is BACTRIM?
Uses
Sulphamethoxazole is antibacterial sulfonamide. Sulphamethoxazole is classified as an intermediate-acting sulfonamide and is longer-actin...
How It Works
Infuse over 60-90 min, must dilute well before giving. May be given less diluted in a central line. Not for IM injection. Maintain adequate fluid intake to prevent crystalluria. Administer around-the-clock every 6-12 hours.
How to Take It
1
Adult · PO
800 mg — 12 hourly
In Combination with trimethoprim 160 mg/day.
2
Child · Oral
25 to 30 mg/kg — 12 hourly
Maintenance, As required
3
Child · Oral
50 to 60 mg/kg — 24 hourly
Initial
Safety Alerts
Neonates, severe renal or hepatic insufficiency, blood dyscrasias
Important Warnings
Avoid in blood disorders, avoid in infants under 6 weeks (except for treatment or prophylaxis of pneumocystis pneumonia) because of the risk of kernicterus, elderly, G6PD deficiency (risk of haemolytic anaemia), maintain adequate fluid intake, predisposition to folate deficiency, predisposition to hyperkalaemia (in adults), hepatic and renal impairment (reduce or space out dosage), severe allergy or asthma, perform regular haematological tests during long term therapy
Discontinue if rash develops
Side Effects
Abdominal discomfortdiarrhoeaheadacheHyperkalaemianausearashvomitingglossitisblood dyscrasiasfolate deficiencyliver changes. Rarely: erythema multiformeLyell syndromeexfoliative dermatitisStevens-Johnson syndromeconvulsions
Drug Interactions
Folate inhibitors
anticoagulants
anticonvulsants
hypoglycaemics
cyclosporin
procainamide
aman-tadine
lamivudine
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Contraindicated or not recommended.
Storage
Inj Store at room temperature. Do not Freeze. Protect from Sunlight. Tab, Susp Store at room temperature. Protect from Sunlight and Moisture.
Price Intelligence
Rs 733.48
DRAP approved maximum price · per pack of 200 · approved 22 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 200Rs 733.48
Should you consider an alternative?
Other options containing Trimethoprim, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Cotrifa
5ml
Rs 20.96
No DRAP alertsAli Industries
Radisulforal
5ml
Rs 25.74
No DRAP alertsRadiant Pharma (Pvt.) Ltd.,
Zolebid
80mg
Rs 28.1
No DRAP alertsHIGHNOON LABORATORIES LTD.
Amoxazol
200mg
Rs 31.86
AMROS PHARMACEUTICALS.
Hicot
5ml
Rs 34.6
No DRAP alertsHizat Pharmaceutical Industry
Supracombin
200mg
Rs 37.36
SEARLE PAKISTAN (PVT.) LTD.
Ostrinped
200mg
Rs 47.49
No DRAP alertsBRYON PHARMACEUTICALS (PVT) LTD.
Primox
10ml
Rs 55.39
ATCO LABORATORIES LIMITED
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
299
brands
270
molecules
0
alerts